| 摘要 |
There is disclosed a method of treating an individual infected with a macrophage pathogen comprising administering an effective amount of a TGF-.beta. antagonist, Macrophage pathogens include any pa thogenic microorganism that replicates within macrophage cell hosts as their exclusive or primary host cells. TGF-.beta. antag onists include blocking antibodies specific for a human TGF-.beta., soluble TGF-.beta. receptors, protease inhibitors that inactiv ate a protease responsible for activating a precursor TGF-.beta. into an active, mature TGF-.beta., and combinations thereof.
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