| 摘要 |
<p>The present invention relates to compounds of general formula (I) as cyclooxygenase-I selective inhibitors, to the pharmaceutically acceptable salts and solvates thereof, and to pharmaceutical compositions containing them. The compounds show an analgesic and antiinflammatory action, while, in patients with pre-existent ulcers and gastrointestinal disturbances, they do not cause any higher incidence of these conditions nor worsen them neither delay the healing thereof. The present invention also relates to a process for the preparation of the compounds as well as to the therapeutic use thereof.</p> |
