| 摘要 |
FIELD: organic chemistry, medicine, pharmacology. SUBSTANCE: invention proposes a compound of the formula (I) <EMI ID=0.232 HE=42 WI=63 TI=CHI> for new application where n = 0 or 1; R is hydroxy-group, methoxy-group, (C<SB>1</SB>-C<SB>7</SB>)-alkanoylhydroxy-group, (C<SB>3</SB>-C<SB>7</SB>)-cycloalkanoyl- -hydroxy-group, (C<SB>1</SB>-C<SB>6</SB>)-alkoxy-(C<SB>1</SB>-C<SB>7</SB>)-alkanoylhydroxy-group, free or substituted aroylhydroxy-group or free or substituted aroyl- -carboxy-group; R is hydrogen atom, hydroxy-group, halogen atom, methoxy-group, (C<SB>1</SB>-C<SB>7</SB>)-alkanoylhydroxy-group, (C<SB>3</SB>-C<SB>7</SB>)-cycloalka- -noylhydroxy-group, (C<SB>1</SB>-C<SB>6</SB>)-alkoxy-(C<SB>1</SB>-C<SB>7</SB>)-alkanoylhydroxy-group, free or substituted aroylhydroxy-group or free or substituted aroylcarboxy-group; R is heterocyclic ring taken from the group involving pyrrolidine, piperidine or hexamethyleneimine group, or its pharmaceutically acceptable salt or solvate used for decrease of blood cholesterol content. Invention proposes a pharmaceutical composition for the same aim based on compound of the general formula (I). EFFECT: broadened pattern of hypocholesterolemic agents. 5 cl, 7 tbli
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