| 摘要 |
PROBLEM TO BE SOLVED: To obtain a new isolated polynucleotide having a high identity to a nucleic acid encoding a human 7-transmembrane receptor polypeptide having a specific amino acid sequence and useful for producing the substance used for treating and diagnosing infectious diseases, cancers, asthma, cardiac infarction, etc. SOLUTION: This new isolated polynucleotide has a nucleotide sequence having at least a 80% identity over the whole length to a nucleotide sequence encoding a human 7-transmembrane receptor polypeptide sequence having an amino acid sequence of the formula, or a nucleotide sequence complementary to the nucleotide sequence, and the polypeptide and the polynucletoide are useful for treating, diagnosing, etc., infectious diseases, aches, cancers, anorexia, polyphagia, asthma, Parkinson's disease, acute heat failures, hypertension, osteoporosis, stenocardia, cardiac infarction, allergies, prostatic hypertrophy, psychosis, etc. The polynucleotide is obtained by screening a cDNA library originated from a human testis cell, etc. |
