发明名称 |
SUBSTITUTED CYCLOBUTYLAMINE DERIVATIVE |
摘要 |
Substituted cyclobutylamine derivatives with novel structures represented by general formula (I), wherein R1 to R4 and Q represent each a specific substituent and, in particular, Q represents a quinolone derivative of a specific structure. These derivatives are useful as antibacterial compounds which have excellent antibacterial actions over a wide scope of bacteria including gram-negative and gram-positive ones, exert potent antibacterial activities particularly on methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae and quinolone-resistant bacteria and are excellent in the in vivo dynamics and safety.
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申请公布号 |
CA2292580(A1) |
申请公布日期 |
1998.12.03 |
申请号 |
CA19982292580 |
申请日期 |
1998.05.28 |
申请人 |
DAIICHI PHARMACEUTICAL CO., LTD. |
发明人 |
MIYAUCHI, RIE;TAKEMURA, MAKOTO;TAKAHASHI, HISASHI;SUGITA, KAZUYUKI |
分类号 |
A61K31/4709;A61P31/04;C07D401/04;C07D498/06;(IPC1-7):C07D401/04 |
主分类号 |
A61K31/4709 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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