发明名称 |
Modified ligands for receptor tyrosine kinases |
摘要 |
The invention provides for synthetic ligands that bind to class I receptor tyrosine kinases. The ligands are analogous in structure to naturally occurring ligands. The modified ligands however, have eliminated the mid-sequence (B) domain present in the native ligands and replaced it with a peptide bridge which links the amino (A) and carboxy (C) domains.
|
申请公布号 |
US5840687(A) |
申请公布日期 |
1998.11.24 |
申请号 |
US19950384714 |
申请日期 |
1995.02.02 |
申请人 |
SCHERING AKTIENGESELLSCHAFT |
发明人 |
HARKINS, RICHARD N.;SETO, MARIAN;KATZ, BRADLEY A. |
分类号 |
C12N15/09;A61K38/00;A61P35/00;A61P43/00;C07K14/495;C12N15/00;C12N15/12;C12R1/91;(IPC1-7):C12P21/02 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|