发明名称 A NOVEL MEMBER OF THE IL-1 FAMILY, IL-1 DELTA
摘要 IL-1 delta polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing IL-1 delta polypeptides and polynucleotides in the design of protocols for the treatm ent of chronic and acute inflammation, arthritis, septicemia, autoimmune diseases (e.g. inflammator y bowel disease, psoriasis), transplant rejection, graft versus host disease, infection, stroke, ischemia, acute respiratory disease syndrome, restenosis, brain injury, AIDS, bone diseases (e.g. osteoporos is), cancer (e.g. lymphoproliferative disorders, atherosclerosis, and Alzheimers's disease, among others, and diagnostic assays for such conditions.
申请公布号 CA2221866(A1) 申请公布日期 1998.11.19
申请号 CA19982221866 申请日期 1998.01.28
申请人 SMITHKLINE BEECHAM CORPORATION 发明人 CONNOR, JANICE R.;YOUNG, PETER R.;JAMES, IAN E.
分类号 C12N15/09;A61K38/00;A61K39/395;A61K48/00;A61P3/06;A61P7/00;A61P9/00;A61P9/10;A61P11/00;A61P25/00;A61P29/00;A61P31/00;A61P31/12;A61P31/18;A61P35/00;A61P37/02;A61P37/06;A61P43/00;C07K14/545;C07K16/24;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/00;C12N15/24;C12N15/25;C12P21/02;C12Q1/02;C12Q1/68;C12R1/91;(IPC1-7):C12N15/25;A61K38/20;G01N33/53;A61K31/70 主分类号 C12N15/09
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