| 摘要 |
This invention relates to a method of treating or reducing cell proliferation in a mammal in need thereof, which comprises administering to said mammal an effective CoA-independent transacylase (CoA-IT) inhibiting amount of a compound of formula (I), wherein the variables of Y, X, m, R3, R4, R10, R20, R5, R6 and R7 are defined in the specification. Figure 3 demonstrates the ability of SB216754, ((3S,4R)-4-(isobutenyloxy)-3-triphenylmethylamino)azetidin-2-one) to decrease the viability of HL-60 cells.
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