摘要 |
PROBLEM TO BE SOLVED: To obtain the subject compound useful for elucidating physiological action of docosahexaenoic acid, having high labeling ratio, high safety, capable of measuring human metabolic experiment and metabolic ability, by culturing a docosahexaenoic acid-producing bacterium in the presence of a<13> C labeled carbon source. SOLUTION: This compound is<13> C labeled docosahexaenoic acid (A) or its ester. For example, the<13> C labeled docosahexaenoic acid (A) is obtained by culturing a bacterium belonging to the genus Shewanella or Pseudoalteromonas, capable of producing docosahexaenoic acid in a medium containing a<13> C labeled carbon source (e.g. sodium acetate, a saccharide, an amino acid or carbon dioxide) (to be concrete, a medium comprising 1% of peptone, 0.2% of yeast essence, 50% of artificial seawater and 0.05-1.0% of<13> C labeled acetic acid). |