发明名称 |
7-PHENYL-1,4-DIAZEPANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
<p>1-Benzoyl-4-aminoacyl-7-phenyl-1,4-diazepine derivatives (I) are new. Also new are four classes of intermediates. 1,4-Diazepine derivatives of formula (I) and their acid addition salts are new. Ph1 = phenyl substituted by R2 and R3; Ph2 = phenyl substituted by R4 and R5; Ph3 = 3-(R6)-5-(R7)-phenyl; R1 = H or alkyl; R2-R5 = H, alkyl, alkoxy, halo or CF3; or R2+R3 or R4+R5 on adjacent C = 1-2C alkylenedioxy; R6,R7 = alkyl, halo or CF3; A = (CH2)n or NH(CH2)m; n = 1-3; m = 2 or 3; and B = 1-3C alkylene chain (optionally substituted by alkyl).</p> |
申请公布号 |
HU9801888(D0) |
申请公布日期 |
1998.10.28 |
申请号 |
HU19980001888 |
申请日期 |
1998.08.17 |
申请人 |
SOLVAY PHARMACEUTICALS GMBH. |
发明人 |
ANTEL,JOCHEN;BIELENBERG,GERHARD-WILHELM;BRUECKNER,REINHARD;DAVID,SAMUEL;EECKHOUT,CHRISTIAN;PECK,MICHAEL;ZIEGLER,DIETER |
分类号 |
A61K31/55;A61P1/00;A61P43/00;C07D243/08 |
主分类号 |
A61K31/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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