发明名称 LHRH-Antagonists in the treatment of fertility disorders
摘要 <p>This inventions relates to the preparation of a medicament to be applied in the field of treating infertility disorders with or without assisted reproduction techniques. In particular the improvement is directed to use an LH-RH Antagonist preferabely Cetrorelix for preparation of an medicament applied in the method of treating infertility disorders by inducing follicle growth by administration of exogenous gonadotropins and in administering the LH-RH Antagonist which contains an amount of LH-RH Antagonist as low as only to suppress endogenous LH but the FSH secretion is maintained at a natural level and the individual estrogen development is not affected. When using the preparation, the follicle development must not be in each case externally stimulated (e.g. by the addition of gonadotropins) but can be maintened by endogenous gonadotropins. Advantageously the preparation can be given in the range of 0.1 to 5 mg of Cetrorelix / day during a multiple dosing posoilogy.</p>
申请公布号 EP0788799(A3) 申请公布日期 1998.10.21
申请号 EP19970100852 申请日期 1997.01.21
申请人 ASTA MEDICA AKTIENGESELLSCHAFT 发明人 ENGEL, JUERGEN PROF. DR.;BOUCHARD, PHILIPPE BOUCHARD, PROF. DR.;FRYDMAN, RENE, PROF. DR.;DIEDRICH, KLAUS PROF. DR. MED.;DEVROEY, PAUL, PROF. DR.
分类号 A61K38/22;A61K38/04;A61K38/09;A61P13/02;A61P15/00;(IPC1-7):A61K38/09 主分类号 A61K38/22
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