USE OF 2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES FOR THE MANUFACTURE OF A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF SLEEP DISORDERS

摘要

The present invention provides novel uses of the compounds of general formula (I) wherein R<3> is hydrogen, alkyl or cycloalkyl; R<4> is hydrogen or R<4> together with R<10> represents a bridge; R<7> is hydroxy or alkoxy; R<10>, R<11>, R<12> independently represent hydrogen, trifluoromethyl, halogen or alkyl; or R<10> together with R<11> represents a bridge, or R<11> together with R<12> represents a bridge, the bridge in both cases being chosen among -O-CH2-CH2-, -O-CH2-CH2-CH2-, -O-CH=CH-, -CH2-CH2-CH2-, -CH2-CH=CH- or -CH2-CH2-CH2-CH2-; R<13> is hydrogen, halogen or alkyl; and pharmaceutically acceptable salts thereof in combination with a pharmaceutically acceptable carrier for the manufacture of a pharmaceutical composition for treatment of sleep disorders and/or sleep disturbances.