METHOD FOR PREDICTING DRUG RESPONSE, IN PARTICULAR IGF-I

摘要

Methods are provided for formulating models for predicting whether subjects will respond to a particular drug or treatment regimen. Biochemical profiles are obtained (by measuring a variety or biochemical parameters) for a test group before and after treatment with the drug or regimen. These values are used to formulate a specific predictive method for the particular drug or treatment regimen. The predictive measurement is then used with biochemical parameters obtained from a subject to predict whether that subject will respond to the particular drug or treatment regimen. The treatment is preferably insulin-like growth factor (IFG-I), in combination with IGFBP-3, and the biochemical parameters are thyroid stimulating hormone and tetraiodothyroine levels.