发明名称 Use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of ginkgolides
摘要 The invention relates to the use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of Ginkgolides. The cyclodextrins used comply with the formula: <IMAGE> (I) in which n is equal to 6, 7 or 8 and the R1, which can be the same or different, represent OH or SR2 with R2 representing a group derived from a monosaccharide or an oligosaccharide. The Ginkgolide is preferably Ginkgolide B.
申请公布号 US5798342(A) 申请公布日期 1998.08.25
申请号 US19960711265 申请日期 1996.09.09
申请人 COMMISSARIAT A L'ENERGIE ATOMIQUE 发明人 DEFAYE, JACQUES;LAINE, VALERIE;DJEDAINI-PILARD, FLORENCE;PERLY, BRUNO
分类号 C07D493/22;A61K31/365;A61K36/00;A61K36/16;A61K47/40;A61K47/48;A61P7/02;A61P43/00;C08B37/00;C08B37/16;(IPC1-7):A61K31/715;A61K31/335 主分类号 C07D493/22
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