发明名称 |
Use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of ginkgolides |
摘要 |
The invention relates to the use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of Ginkgolides. The cyclodextrins used comply with the formula: <IMAGE> (I) in which n is equal to 6, 7 or 8 and the R1, which can be the same or different, represent OH or SR2 with R2 representing a group derived from a monosaccharide or an oligosaccharide. The Ginkgolide is preferably Ginkgolide B.
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申请公布号 |
US5798342(A) |
申请公布日期 |
1998.08.25 |
申请号 |
US19960711265 |
申请日期 |
1996.09.09 |
申请人 |
COMMISSARIAT A L'ENERGIE ATOMIQUE |
发明人 |
DEFAYE, JACQUES;LAINE, VALERIE;DJEDAINI-PILARD, FLORENCE;PERLY, BRUNO |
分类号 |
C07D493/22;A61K31/365;A61K36/00;A61K36/16;A61K47/40;A61K47/48;A61P7/02;A61P43/00;C08B37/00;C08B37/16;(IPC1-7):A61K31/715;A61K31/335 |
主分类号 |
C07D493/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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