摘要 |
<p>Hexahydroindenopyridine compounds having formula (I) and relative stereochemistry where R1 is C¿1-6? alkyl; R?2¿ is hydrogen or C¿1-6? alkyl; R?3¿ is carboxyl or a group which is metabolized to a carboxyl group under mammalian physiological conditions; R4 is halogen; mixtures of said compound and acid addition salts thereof exhibit potent antispermatogenic activity and are useful in a method or inhibiting spermatogenesis in mammals.</p> |