发明名称 |
Composite surgical material |
摘要 |
A composite surgical material comprising a collagen matrix reinforced by a layer of a synthetic bioabsorbable material such as polylactide/polyglycolide or oxidized regenerated cellulose, and wherein oil droplets are dispersed in the collagen matrix. The oil droplets comprise 1% to 75% of the weight of the composite and result in improved leak-proofing of the composite. The composite, in the form of a sheet or a tube, is especially useful as a temporary, fully bioabsorbable prosthesis, for membranes or blood vessels where a highly leak-proof prosthesis is required. The invention also provides a method of making a composite surgical material comprising the steps of: providing a layer of a synthetic bioabsorbable material; providing a dispersion of collagen in an oil-in-water emulsion; coating at least one face of the layer of synthetic bioabsorbable material with the said dispersion; and drying the composite material thus obtained.
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申请公布号 |
US5789465(A) |
申请公布日期 |
1998.08.04 |
申请号 |
US19940280916 |
申请日期 |
1994.07.27 |
申请人 |
JOHNSON & JOHNSON MEDICAL, INC. |
发明人 |
HARVEY, WILSON;LIGHT, NICHOLAS D.;HAYNES, CARLA A. |
分类号 |
A61K9/70;A61F2/02;A61F2/06;A61K6/00;A61K9/00;A61K31/65;A61K31/70;A61K45/00;A61K47/34;A61K47/42;A61L15/00;A61L27/48;A61L27/50;A61L31/00;A61L31/12;A61L31/14;A61P1/00;A61P31/04;(IPC1-7):A61F2/00;A01N25/34 |
主分类号 |
A61K9/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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