发明名称 Alkylated styrenes as prodrugs to COX-2 inhibitors
摘要 The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. <IMAGE> I The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.
申请公布号 US5789413(A) 申请公布日期 1998.08.04
申请号 US19970786517 申请日期 1997.01.21
申请人 MERCK FROSST CANADA, INC. 发明人 BLACK, CAMERON;GRIMM, ERICH;LEGER, SERGE;HUGHES, GREG;PRASIT, PETPIBOON;WANG, ZHAOYIN
分类号 C07C311/29;C07C317/22;C07C317/24;C07C317/44;C07C317/46;C07D307/58;C07D307/60;C07D307/64;C07D307/66;C07D307/94;C07D405/12;(IPC1-7):A61K31/10;A61K31/165;C07C59/42;C07C317/14 主分类号 C07C311/29
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