发明名称 |
BIS[(1,2,3,6-TETRAHYDROPYRROLO[3,2-E]INDOL-3-YL)-ACRYLAMIDE] DERIVATIVES AND PROCESS FOR PRODUCING THE SAME |
摘要 |
Acrylamide derivatives represented by General Formula (1) below: <CHEM> (One specific example of General Formula (1) is methyl (S,S)-3,3,-Ä3,3'-(1,4-phenylenediacryloyl)Ü-bisÄ1-chloromethyl-5-hydro xy-7-trifluoromethyl-1,2,3,6-tetrahydropyrroloÄ3,2-eÜindole-8- carboxylate.) The acrylamide derivatives represented by General Formula (1) is highly selective to cancer cells, less toxic, and highly active also against solid tumor. |
申请公布号 |
HUT77654(A) |
申请公布日期 |
1998.07.28 |
申请号 |
HU19980000067 |
申请日期 |
1995.11.28 |
申请人 |
KYORIN PHARMACEUTICAL CO.,LTD.;SAGAMI CHEMICAL RESEARCH CENTER |
发明人 |
EBISU,HIROYUKI;FUKUDA,YASUMICHI;OOMORI,YASUO;SETO,SIGEKI;TERASHIMA,SHIRO |
分类号 |
C07D519/00 |
主分类号 |
C07D519/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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