发明名称 Chemokine expressed in a mixed lymphocyte reaction
摘要 The present invention provides nucleotide and amino acid sequences that identify and encode TMEC, a novel human lymphotactin expressed in T-cell mixed lymphocyte reaction (TMLR). The present invention also provides for polymerase chain reaction oligomers or hybridization probes for the detection of nucleotide sequences encoding TMEC or TMEC-like molecules, antisense molecules to the nucleotide sequences which encode TMEC, diagnostic tests based on TMEC encoding nucleic acid molecules, genetically engineered expression vectors and host cells for the production of purified TMEC, antibodies capable of binding specifically to TMEC, antagonists and inhibitors with specific binding activity for TMEC, and treatment methods.
申请公布号 US5780268(A) 申请公布日期 1998.07.14
申请号 US19950567816 申请日期 1995.12.06
申请人 INCYTE PHARMACEUTICALS 发明人 COLEMAN, ROGER;GUEGLER, KARL J.;SEILHAMER, JEFFREY J.
分类号 A61K38/00;C07K14/52;C12N15/19;(IPC1-7):C12N15/19;C12N15/85;C12N5/06 主分类号 A61K38/00
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