发明名称 |
Method and device for chlamydia detection |
摘要 |
A lateral flow assay device for detecting the presence of Chlamydia antigen in patient's samples comprises a flow matrix including a labelling zone and a capture zone. Labelling complex comprising antibodies specific for an epitope on the lipopolysaccharide antigen of Chlamydia is present within the labelling zone. Immobilized antibody specific for the same or another epitope of the lipopolysaccharide antigen of Chlamydia is located in the capture zone. The sample containing the Chlamydia antigen will flow first through the labelling zone, where it complexes with the labelling complex, and then to the capture zone, where it is captured by the immobilized antibody. Chlamydia antigen may be extracted from a patient sample, such as a endocervical swab, by first extracting the antigen in a strong base followed by neutralization with a zwitterionic detergent and a blocking protein present in a zwitterionic buffer.
|
申请公布号 |
US5773234(A) |
申请公布日期 |
1998.06.30 |
申请号 |
US19950511337 |
申请日期 |
1995.08.07 |
申请人 |
QUIDEL CORPORATION |
发明人 |
PRONOVOST, ALLAN D.;KLEPPER, ROBERT E.;PAWLAK, CATHERINE |
分类号 |
G01N33/558;G01N33/569;(IPC1-7):G01N33/53 |
主分类号 |
G01N33/558 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|