摘要 |
The invention concerns a method for inducing a selective collapse of the vasculature of a solid tumor by administering to a patient a therapeutically effective dose of a combination of a compound preventing the formation of a functional thrombin-thrombomodulin complex and a cytokine selected from the group of TNF- beta (LT), TNF- alpha , IL-1, and IFN- gamma . The invention further concerns the composition used in this method.
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