摘要 |
<p>A method determining the number of repeats in a tandem repeat sequence of a nucleic acid target comprises providing an array of nucleic acid probes immobilised at spaced locations on a surface of a support. Each probe of the array has a tandem repeat sequence complementary to that in the target and containing a different number of repeats. When the target is hybridised with the array and forms a perfect match with the probe having the same number of repeats in the tandem repeat sequence, it is not removed by exonuclease treatment and can be detected on the array.</p> |