发明名称 |
Aminosilane/carbodiimide coupling of DNA to glass substrate |
摘要 |
A method for coupling DNA to a glass substrate by aminating the glass substrate with an aminosilane, reacting DNA with a carbodiimide/imidazole solution to create a 5'-phosphorimidazolide, and reacting the aminated glass substrate and phosphorimidazolide to couple the DNA to the substrate.
|
申请公布号 |
US5760130(A) |
申请公布日期 |
1998.06.02 |
申请号 |
US19970854989 |
申请日期 |
1997.05.13 |
申请人 |
MOLECULAR DYNAMICS, INC. |
发明人 |
JOHNSTON, RICHARD F.;TROUNSTINE, MARY |
分类号 |
C07H21/00;C12Q1/68;(IPC1-7):C08G63/48;C08G63/91 |
主分类号 |
C07H21/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|