摘要 |
Oxygenic heterocyclic compounds represented by general formula (I) or pharmacologically acceptable salts thereof, wherein n is an integer of 1 to 4; R1, R2, R3 and R4 are the same or diffrent and each represents hydrogen, optionally substituted lower alkyl, etc.; R5 represents hydrogen or halogeno; R6 represents hydroxy or optionally substituted lower alkoxy; D represents (1): -C(R8)(R9)-X- or bond (2): -Y-ZR14; and R7 represents (1), optionally substituted lower alkyl, optionally substituted cycloalkyl, polycycloalkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted aromatic heterocycle, optionally substituted heterocycle, or pyridine N-oxide, (2), (3): -Y-Z-(CH2)m-N(R16a)R16b, or (4): -Y-CON(R17a)R17b.
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申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
NAKASATO, YOSHISUKE;YANAGAWA, KOJI;ISHII, HIDEE;OHSHIMA, ETSUO;MANABE, HARUHIKO;ICHIMURA, MICHIO;SATO, SOICHIRO;KOIKE, RIE |