发明名称 METHODS OF TREATING OR PREVENTING CARDIAC ARRHYTHMIA
摘要 This application discloses a method of treating or preventing atrial arrhythmias which utilizes compounds which are blockers of the ultra-rapidly-activating delayed rectifier K+ current (IKur) of the human atrium in a usedependent and/or rate dependent manner, and which provide the selective block preferentially at fast heart rates so that the effect is realized or maximized when required.
申请公布号 CA2268942(A1) 申请公布日期 1998.05.07
申请号 CA19972268942 申请日期 1997.10.29
申请人 MERCK & CO., INC. 发明人 FERMINI, BERNARD;SWANSON, RICHARD J.;LYNCH, JOSEPH J., JR.;SALATA, JOSEPH J.
分类号 C07D237/24;A61K31/00;A61K31/50;A61K31/66;A61K45/00;A61P9/00;A61P9/06;A61P43/00;C07F9/53;(IPC1-7):A61K31/66 主分类号 C07D237/24
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