发明名称 |
METHODS OF TREATING OR PREVENTING CARDIAC ARRHYTHMIA |
摘要 |
This application discloses a method of treating or preventing atrial arrhythmias which utilizes compounds which are blockers of the ultra-rapidly-activating delayed rectifier K+ current (IKur) of the human atrium in a usedependent and/or rate dependent manner, and which provide the selective block preferentially at fast heart rates so that the effect is realized or maximized when required.
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申请公布号 |
CA2268942(A1) |
申请公布日期 |
1998.05.07 |
申请号 |
CA19972268942 |
申请日期 |
1997.10.29 |
申请人 |
MERCK & CO., INC. |
发明人 |
FERMINI, BERNARD;SWANSON, RICHARD J.;LYNCH, JOSEPH J., JR.;SALATA, JOSEPH J. |
分类号 |
C07D237/24;A61K31/00;A61K31/50;A61K31/66;A61K45/00;A61P9/00;A61P9/06;A61P43/00;C07F9/53;(IPC1-7):A61K31/66 |
主分类号 |
C07D237/24 |
代理机构 |
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代理人 |
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地址 |
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