摘要 |
<p>The plant Parthenium integrifolium or parts thereof or an extract or component thereof can be used for preparing medicines for the enhancement of the TH2 pathway of the immune system, the enhancement of the levels of interleukin-4 and interleukin-10, the selective suppression of cyclooxygenase-2 (COX-2), and more specifically for the alleviation of pain, in particular migraine or headache, and for the treatment or prevention of inflammatory or autoimmune disorders. Extracts of the plant can i.a. be obtained by extraction or by steam or vacuum distillation of fresh or dried Parthenium integrifolium or parts thereof, preferably the root. Extraction may be performed with a number of different organic solvents, preferably water miscible solvents, and mixtures thereof with water. After the primary extraction process a second step of processing, such as liquid-liquid extraction, column chromatography, steam distillation or vacuum distillation, can be employed to remove or to concentrate and possibly isolate any constituent of the extract.</p> |