| 摘要 |
PCT No. PCT/US95/05938 Sec. 371 Date Sep. 26, 1996 Sec. 102(e) Date Sep. 26, 1996 PCT Filed May 12, 1995 PCT Pub. No. WO95/32710 PCT Pub. Date Dec. 7, 1995Compounds of the following general structure X-Y-Z-Aryl-A-B, for example, <IMAGE> which inhibit osteoclast mediated bone resorption. Specifically, the compounds are useful for treating mammals suffering from a bone condition caused or mediated by increased bone resorption, who are in need of such therapy. The compounds may be administered in oral dosage forms such as tablets, capsules, e.g. sustained release capsules, powders, granules, and suspensions.
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