发明名称 FLAVONOID GLUCOSIDE AND 5-LIPOXYGENASE INHIBITOR CONTAINING THE FLAVONOID AS ACTIVE INGREDIENT
摘要 NEW MATERIAL:A comround of the formula (R1 is rhamnose<3-1>xylose, rhamnose<2-1>fucose; R2 is H, glucose; R3 is H, methyl). EXAMPLE:4'-Methoxy-5-hydroxy-8-(3,3-dimethylallyl)flavon 3-0-beta-D-xylopyranosyl(1 3)-4-0-acetyl-alpha-L-rhamnopyranoside-7-0-beta-D-glucoside. USE:A 5-lipoxygenase inhibitor. Useful as an antiallergic drug, antiinflammatory drug, etc. PREPARATION:The stems and leaves of Epimedium koreanum NAKAI are extracted with a solvent such as acetone, and the solvent is removed from the extraction solution. The residue is subjected to a column chromatography, etc., using hexane, etc., as an elution solvent.
申请公布号 JPH04159295(A) 申请公布日期 1992.06.02
申请号 JP19900284308 申请日期 1990.10.24
申请人 TSUMURA & CO 发明人 UEDA TOMOKO;NAKAJIMA KAORU;CHIN MASAO;MIHASHI HIROSHI
分类号 C07H17/07;A61K31/70;A61K31/7042;A61K31/7048;A61K36/18;A61P29/00;A61P37/08 主分类号 C07H17/07
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