PERCUTANEOUS PREPARATIONS

摘要

Percutaneous preparations composed of a support and a plaster layer located on one face thereof and containing 2-tert-butylamino-1-(2-chloro-4-hydroxy-phenyl)ethan-1-o1 or its pharmacologically acceptable salt and a pressure-sensitive adhesive, wherein the adhesive is an acrylic polymer substantially free from carboxy or comprises a material containing at least one high-molecular-weight rubber component with an average molecular weight of from 300,000 to 2,500,000 and at least one additive selected from among C12-18 fatty acid esters, C8-10 fatty acid monoglycerides and C6-10 dibasic acid esters. These percutaneous preparations are excellent in percutaneous drug-absorption properties, can give long-lasting drug effects with little side effect and, therefore, are useful in the prevention and treatment of threatened abortion, premature birth, urination disorders such as urinary incontinence, etc.