发明名称 |
Benzoheterocyclic compounds |
摘要 |
<p>The present invention relates to a compound selected from the group consisting of the compounds of the following formulae: <CHEM> wherein R<1> is a cyclopropyl group which may be substituted by 1 to 3 of substituents selected from the group consisting of a lower alkyl group and a halogen atom, a phenyl group which may be substituted by 1 to 3 of substituents selected from the group consisting of a lower alkoxy group, a halogen atom and a hydroxy group on phenyl ring, a lower alkyl group which may be substituted by a halogen atom, a lower alkanoyloxy group or a hydroxy group, a lower alkenyl group, or a thienyl group; R<2'> is a halogen atom or a 5- to 9-membered saturated or unsaturated heterocyclic group which may be substituted; R<3> is a hydrogen atom, a lower alkyl group or a halogen atom; R<3'> is a group of the formula: -CH(R<20>)SR<21> (R<20> and R<21> are as defined hereinafter) or R<3>; R<4> is a lower alkyl group or a halogen atom; R<5> is a group of the formula: -COR<10> (R<10> is a lower alkyl group) or a group of the formula: -COOR<11> (R<11> is a lower alkyl group); R<6> is a lower alkyl group; R<7> is a group of the formula: -NR<12>R<13> (R<12> and R<13> are each a lower alkyl group) or a lower alkoxy group; R<20> is a hydrogen atom or a lower alkyl group; R<21> is a lower alkyl group; R<25>, R<27> and R<28> are each a lower alkyl group; R<32> is a lower alkyl; and X, X<2>, X<3>, X<4> and X<7> are each a halogen atom.</p> |
申请公布号 |
EP0823413(A2) |
申请公布日期 |
1998.02.11 |
申请号 |
EP19970120444 |
申请日期 |
1988.04.14 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
UEDA, HIRAKI;MIYAMOTO, HISASHI;YAMASHITA, HIROSHI;TONE, HITOSHI |
分类号 |
C07C211/47;C07C211/52;C07C229/30;C07C229/34;C07C321/16;C07C323/29;C07D207/09;C07D207/14;C07D215/22;C07D241/04;C07D295/04;C07D295/16;C07D319/06;C07D401/04;C07D405/06;C07D405/12;C07D409/04;C07D413/04;C07D487/04;C07D491/04;C07D498/04;C07D498/06;C07F5/04;C07D215/56;A61K31/47;A61K31/495;A61K31/535;A61K31/5375;A61K31/54;A61K31/55;A61P31/04;C07C25/02;C07C25/13;C07C63/04;C07C63/06;C07C63/70;C07C69/716;C07C69/738;C07C205/11;C07C205/12;(IPC1-7):C07C69/716 |
主分类号 |
C07C211/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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