TYROSINE KINASE ASSOCIATED PROTEIN-1 (TKA-1), NUCLEOTIDE AND AMINO ACID SEQUENCES AND THEIR USE IN DIAGNOSIS AND TREATMENT OF TKA-1 RELATED DISORDERS

摘要

The present invention relates to TKA-1 polypeptides, nucleic acids encoding such polypeptides, cells, tissues and animals containing such nucleic acids, antibodies to such polypeptides, assays utilizing such polypeptides, and methods relating to all of the foregoing. Methods for treatment, diagnosis, and screening are provided for TKA-1 related diseases or conditions characterized by an abnormal interaction between a TKA-1 polypeptide and a TKA-1 binding partner.