| 发明名称 |
NOVEL METHODS AND COMPOSITIONS FOR COMBINATORIAL-BASED DISCOVERY OF NEW MULTIMERIC MOLECULES |
| 摘要 |
The present invention provides methods and compositions for producing and screening combinatorial libraries of multimeric proteins. The present invention relies on the use of filamentous fungal heterokaryons that are produced using two or more parent strains into which a population of DNA molecules encoding variants of a multimeric protein have been introduced.
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| 申请公布号 |
CA2260360(A1) |
申请公布日期 |
1998.01.15 |
| 申请号 |
CA19972260360 |
申请日期 |
1997.06.30 |
| 申请人 |
UNIVERSITY OF HAWAII |
发明人 |
STUART, W. DORSEY |
| 分类号 |
C12N15/09;C07K14/59;C12N1/15;C12N15/04;C12N15/10;C12N15/16;C12P21/02;C12P21/04;C12P21/08;C12R1/645;C40B40/02;G01N33/15;G01N33/50;G01N33/566;(IPC1-7):C12N1/15;G01N33/53 |
主分类号 |
C12N15/09 |
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