| 发明名称 |
Heterocyclic-esters or -amides used as 5-HT4 receptor antagonists |
| 摘要 |
PCT No. PCT/EP93/02775 Sec. 371 Date Apr. 11, 1995 Sec. 102(e) Date Apr. 11, 1995 PCT Filed Oct. 8, 1993 PCT Pub. No. WO94/08994 PCT Pub. Date Apr. 28, 1994Compounds of formula (I), wherein formula I consists of formulae (I-1) to (I-4), which are defined in the specification, and pharmaceutically acceptable salts thereof, and the use of a compound of formula I or a pharmaceutically acceptable salt thereof, and their use as pharmaceuticals in the treatment of gastrointestinal disorders, cardiovascular disorders and CNS disorder.
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| 申请公布号 |
US5708174(A) |
申请公布日期 |
1998.01.13 |
| 申请号 |
US19950416773 |
申请日期 |
1995.04.11 |
| 申请人 |
SMITHKLINE BEECHAM P.L.C. |
发明人 |
KING, FRANCIS DAVID;GASTER, LARAMIE MARY;JOINER, GRAHAM FRANCIS;MULHOLLAND, KEITH RAYMOND;RAHMAN, SHIRLEY KATHERINE |
| 分类号 |
A61K31/4427;A61K31/443;A61K31/4433;A61K31/445;A61K31/47;A61P1/00;A61P9/00;A61P43/00;C07D401/12;C07D405/12;C07D409/12;C07D455/02;(IPC1-7):C07D215/227;C07D215/06 |
主分类号 |
A61K31/4427 |
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