| 摘要 |
<p>Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula (I) wherein: R' is hydrogen, methyl or NH2C(O)CH2-; R" and R''' are independently methyl or hydrogen; Rx1, Rx2, Ry1, Ry2, Ry3, and Ry4 are independently hydroxy or hydrogen; R0 is a group of formula (1); R1 is C1-C6 alkyl, C1-C6 alkoxy, phenyl, p-halo-phenyl, p-nitrophenyl, phenoxy, benzyl, p-halo-benzyl, or p-nitro-benzyl; and R2 is an acyl side chain as defined herein.</p> |
