发明名称 |
RECOGNITION MOLECULES INTERACTING SPECIFICALLY WITH THE ACTIVE SITE OR CLEFT OF A TARGET MOLECULE |
摘要 |
The invention relates to a recognition molecule, being capable of interacting with an active site or cleft of a target molecule, which recognition molecule comprises an exposed loop structure, which extends from a basic recognition unit. The loop structure is for example the CDR3 of a camelid species heavy chain antibody having a binding specificity fo the active site or cleft of a target molecule, or a derived version of such a CDR3. The basic recognition unit is for example formed by an antibody-type structure having binding affinity for the target molecule.
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申请公布号 |
CA2258518(A1) |
申请公布日期 |
1997.12.31 |
申请号 |
CA19972258518 |
申请日期 |
1997.06.27 |
申请人 |
VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW |
发明人 |
WYNS, LODE;MUYLDERMANS, SERGE |
分类号 |
G01N33/531;A61K38/00;A61K39/00;A61K39/395;A61K45/00;A61P39/02;A61P43/00;C07K16/00;C07K16/12;C07K16/18;C07K16/40;C12N15/09;C12N15/10;C12N15/62;C12P21/02;C12R1/19;G01N33/50;(IPC1-7):C07K16/00;A61K49/00;C07K19/00;A61K51/10;C07K1/22;C07K16/28;A61K47/48;G01N33/53 |
主分类号 |
G01N33/531 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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