SUBSTANCES FOR TREATING LEPTIN PATHWAY ABNORMALITIES

摘要

A composition for diagnosing or treating abnormalities in the endogenous leptin pathway in a subject mammal consisting essentially of apolipoprotein J bound to leptin or comprising a purified form of apolipoprotein J bound to leptin. A method for diagnosing abnormalities in the endogenous leptin pathway in a subject mammal. A method for treating abnormalities in the endogenous leptin pathway in a subject mammal. A method for determining the presence or amount of leptin that is associated with apolipoprotein J in a test sample. A kit for performing the method for determining the presence or amount of leptin that is associated with apolipoprotein J in a test sample.