| 摘要 |
<p>A cyclic lipopeptide acylase which can effectively remove acyl side chains from cyclic lipopeptides, specifically substances FR901379 of general formula (I) and analogues thereof; and a process for the preparation of cyclic peptides by the use of this acylase, wherein R1 is acyl; R2 is hydroxyl or acyloxy; R3 is H or hydroxyl; R4 is H or hydroxyl; R5 is H or hydroxysulfonyloxy; and R6 is H or carbamoyl.</p> |
