Isolated cytolytic T cells specific for complexes of MAGE related peptides and HLA molecules
摘要
The invention involves a nonapeptide derived from the tumor rejection antigen precursor encoded by gene MAGE-3. This nonapeptide is presented by HLA molecules HLA-A1. The resulting complexes are identified by cytolytic T cells. Such recognition may be used in diagnostics, or therapeutically.
申请公布号
US5695994(A)
申请公布日期
1997.12.09
申请号
US19950443341
申请日期
1995.05.17
申请人
LUDWIG INSTITUTE FOR CANCER RESEARCH
发明人
BOON-FALLEUR, THIERRY;VAN DER BRUGGEN, PIERRE;DE PLAEN, ETIENNE;LURGUIN, CHRISTOPHE;TRAVERSARI, CATIA;GAUGLER, BEATRICE;VAN DEN EYNDE, BENOIT
