| 发明名称 |
PIPERAZINE DERIVATIVES AS 5-HT ANTAGONISTS. |
| 摘要 |
<p>PCT No. PCT/GB93/02661 Sec. 371 Date May 24, 1995 Sec. 102(e) Date May 24, 1995 PCT Filed Dec. 24, 1993 PCT Pub. No. WO94/15928 PCT Pub. Date Jul. 21, 1994Piperazine derivatives of formula (I) and their pharmaceutically acceptable salts are 5-HT1A binding agents and may be used, for example, as anxiolytics. In the formula, R and R3 are hydrogen or lower alkyl or R3 is spirocycloalkyl, R1 and R2 are aryl or heteroaryl radicals and n is 1 or 2 and m is 1 to 3 and the total of n+m is 2-4. <IMAGE> (I)</p> |
| 申请公布号 |
GR3024430(T3) |
申请公布日期 |
1997.11.28 |
| 申请号 |
GR19970402073T |
申请日期 |
1997.08.13 |
| 申请人 |
JOHN WYETH & BROTHER LIMITED |
发明人 |
WARD, TERENCE, JAMES;ASHWELL, MARK, ANTONY |
| 分类号 |
C07D295/08;A61K31/495;A61P43/00;C07D213/30;C07D213/36;C07D217/22;C07D239/42;C07D295/096;(IPC1-7):C07D295/08;C07D295/02;C07D213/38 |
主分类号 |
C07D295/08 |
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