发明名称 REGULATING METABOLISM BY MODIFYING THE LEVEL OF TREHALOSE-6-PHOSPHATE
摘要 <p>The invention lies in the field of regulation of carbon flow in the metabolism of the cell. It has been found that induction of a change in the intracellular availability of the saccharide trehalose-6-phosphate (T-6-P) induces modifications of the development and/or composition of cells, tissue and organs in vivo. These changes can be induced by introducing or inhibiting the enzymes trehalose phosphate synthase (TPS) which is capable of forming T-6-P and trehalose phosphate phosphatase (TPP) which degrades T-6-P into trehalose. The carbon flow through the glycolysis will be stimulated by a decrease in the intracellular level of T-6-P.</p>
申请公布号 WO1997042326(A2) 申请公布日期 1997.11.13
申请号 EP1997002497 申请日期 1997.05.02
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