| 摘要 |
<p>Preparation of fluorinated aromatic compounds of formula (I) comprises direct fluorination of aromatic compounds of formula (II) with fluorine (F2) in a reaction medium containing a polyfluoroalkanesulphonic acid of formula CFnH(3-n)(CFY)m-SO3H (III). X = COOH, COOR, CONH2, CONR<1>R<2>, CF3, CN, CHO, NO2 or NH2; Y = F, Cl, OCH3, OCF3, OCCl3, p-NO2-C6H4, p-NO2-C6H4-O or OH; Z = H, F, Cl, CF3, CCl3 or OCH3; R, R<1>, R<2> = 1-6 C alkyl with 0-3 halogen substituents; m = 0-5; n = 1 - 3; Y' = F, Cl, H or R'FY"; Y" = F, Cl or H; R' = 1-3 C alkylene, which may be partly or completely fluorinated. Also claimed is the use of (III) in a reaction medium or as reaction medium in direct fluorination of (II).</p> |
