| 摘要 |
<p>Hemoglobin solutions intended for parenteral administration are stabilized against oxidation of the heme iron to the ferric oxidation state by adding stabilizer compounds to the solutions. The stabilizer compounds are generally alpha-hydroxycarboxylic acids and their salts. The particular compounds are selected for their efficacy in defined temperature ranges, and for their ability to retard methemoglobin formation both in solution and in the frozen state.</p> |
