发明名称 |
Methods for producing enhanced antigenic campylobacter bacteria and vaccines |
摘要 |
Methods using in vitro processes are disclosed for inducing or enhancing expression of enteric bacterial antigens or virulence factors. The methods, therefore, produce antigenically enhanced enteric bacteria. Also disclosed are methods for using the antigenically enhanced bacteria, as well as vaccines containing the enteric bacteria. Specifically, a whole enteric bacteria or components thereof are provided by Campylobacter species. In addition to this species there are other enteric bacteria, such as Helicobacter pylori, which are useful for inducing or enhancing expression of enteric bacterial antigens and/or virulence factors.
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申请公布号 |
US5679564(A) |
申请公布日期 |
1997.10.21 |
申请号 |
US19950538545 |
申请日期 |
1995.10.03 |
申请人 |
ANTEX BIOLOGICS, INC. |
发明人 |
PACE, JOHN LEE;WALKER, RICHARD IVES;FREY, STEVEN MICHAEL |
分类号 |
A61P31/04;C12N1/20;C12Q1/04;C12Q1/18;G01N33/569;(IPC1-7):A01N63/00;A61K39/38;A61K45/00 |
主分类号 |
A61P31/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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