发明名称 |
3,4-disubstituted phenylethanolaminotetralincarboxylate derivatives |
摘要 |
The present invention relates to 3,4-disubstituted phenylethanolaminotetralincarboxylic acid derivatives represented by the general formula: <CHEM> Äwherein Q represents a vinylene group or a group represented by the general formula: -A-(CH2)m- (wherein A represents an oxygen atom or a methylene group; and m is an integer of from 1 to 6); R represents a hydrogen atom or a lower alkyl group; n is an integer of 1 or 2; the carbon atom marked with * represents a carbon atom in R configuration, S configuration or a mixture thereof; and the carbon atom marked with (S) represents a carbon atom in S configurationÜ and pharmaceutically acceptable salts thereof, which have a selective beta 2-adrenergic receptor stimulating effect with relieved burdens on the heart such as tachycardia and are useful as an agent for the prevention of threatened abortion and premature labor, a bronchodilator and an agent for pain remission and promoting stone removal in urolithiasis. |
申请公布号 |
AU2176197(A) |
申请公布日期 |
1997.10.17 |
申请号 |
AU19970021761 |
申请日期 |
1997.03.26 |
申请人 |
KISSEI PHARMACEUTICAL CO. LTD. |
发明人 |
MAKIO KITAZAWA;KOSUKE OKAZAKI;TETSURO TAMAI;MASARU SAITO;NOBUYUKI TANAKA;HIROAKI KOBAYASHI;KEN KIKUCHI;HIDEYUKI MURANAKA |
分类号 |
C07C217/74;C07C229/46;C07C229/50 |
主分类号 |
C07C217/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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