发明名称 Anti-cancer composition comprising rhodacyanine compound and cyclodextrin
摘要 An anti-cancer composition comprising a rhodacyanine compound and cyclodextrin or derivative thereof, wherein said rhodacyanine compound is selected from the group consisting of compounds represented by the following Formula (I), the cation moiety of which has a log P value of 4.5-12: <IMAGE> (I) <IMAGE> wherein X1 and X2, which may be the same or different, each represents O, S, Se, <IMAGE> Y1 represents O, S, Se, or <IMAGE> R1 and R3, which may be the same or different, each represents an alkyl group; R2 represents an alkyl group, an aryl group or a heterocyclic group; Z1 and Z2, which may be the same or different, each represents an atomic group necessary to form a 5- or 6-membered ring; L1, L2 and L3, which may be the same or different, each represents a methine group or nitrogen atom and L1 and R3 may combine and form a 5- or 6-membered ring; R4 and R5, which may be the same or different, each represents an alkyl group; R6 and R7, which may be the same or different, each represents an alkyl group or an aryl group; Q represents a pharmaceutically acceptable anion; j and k, which may be the same or different, each represents 1 or 2; m and n, which may be the same or different, each represents 0 or 1.
申请公布号 US5670530(A) 申请公布日期 1997.09.23
申请号 US19950474974 申请日期 1995.06.07
申请人 FUJI PHOTO FILM CO., LTD.;DANA FARBER CANCER INSTITUTE 发明人 CHEN, LAN BO;SHISHIDO, TADAO
分类号 A61K31/41;A61K9/08;A61K31/415;A61K31/42;A61K31/425;A61K31/427;A61K31/428;A61K31/429;A61K31/437;A61K31/4439;A61K31/4709;A61K47/40;A61K47/48;A61P35/00;C07D277/64;C07D277/84;C07D417/12;C07D421/06;C07D513/04;(IPC1-7):A61K31/425 主分类号 A61K31/41
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