| 摘要 |
<p>A method for culturing cells having angiogenic potential in order to induce vascular morphogenesis in said cells is disclosed. According to the method, (a) a cell preparation containing cells having angiogenic potential is prepared; (b) the cells are contacted with a collagen gel containing type III collagen or consisting entirely of type III collagen, in the presence of a suitable culture medium for said cells; and (c) the cells are allowed to develop in the collagen gel for a sufficient time to enable vascular morphogenesis. In vitro vascular morphogenesis models, and the use thereof, in particular for drug screening and for diagnosing diseases with a vascular component in humans and animals, are also disclosed.</p> |
