发明名称 NOVEL ADMINISTRATION OF THROMBOPOIETIN
摘要 The present invention is directed to the surprising and unexpected finding that biologically active thrombopoietin materials can be administered with substantial therapeutic effect at dosage rates commensurate with previously reported administration of such materials, but in a single or low-multiple daily administration. Thus, the predicate of the present invention relates to the reversal of thrombocytopenia by administering to a patient having or in need of such treatment a single or low-multiple daily dose of a therapeutically effective amount of a thrombopoietin. The preferable dose of the active material ranges from about 1 to about 10 .mu.g/kg body weight.
申请公布号 CA2242417(A1) 申请公布日期 1997.07.31
申请号 CA19972242417 申请日期 1997.01.13
申请人 GENENTECH, INC 发明人 THOMAS, GRIFFITH R.
分类号 C12N15/09;A61K31/00;A61K38/00;A61K38/19;A61K38/54;A61P7/00;C07K14/52;C12P21/02;(IPC1-7):A61K38/19;A61K47/48 主分类号 C12N15/09
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