摘要 |
<p>A phosphonate nucleotide compound having antiviral activity and is useful for an orally available and highly safe antiviral agent, which is represented by the following formula (I): <CHEM> wherein R<1> represents hydrogen, a C1-C6 alkoxy, a halogen-substituted C1-C4 alkoxy, halogen, amino, or nitro; R<2> and R<3> independently represent hydrogen, a C1-C22 alkyl, an acyloxymethy, an acylthioethyl, or a halogen-substituted ethyl; R<4> represents hydrogen, a C1-C4 alkyl, a C1-C4 hydroxyalkyl, or a halogen-substituted C1-C4 alkyl; and X represents carbon or nitrogen.</p> |
申请人 |
MITSUBISHI CHEMICAL CORPORATION |
发明人 |
UBASAWA, MASARU;SEKIYA, KOUICHI;TAKASHIMA, HIDEAKI;UEDA, NAOKO;YUASA, SATOSHI;KAMIYA, NAOHIRO |