THERAPEUTIC AGENT FOR CARDIAC FAILURE

摘要

A therapeutic agent for cardiac failure comprising as the active ingredient either a benzopyran derivative represented by general formula (I) or a pharmacologically acceptable salt thereof, wherein R<1> and R<2> each independently represent hydrogen, halogeno, nitro, cyano, amino, C1-6 alkylcarbonylamino, etc.; R<3> and R<4> each independently represents hydrogen, C1-6 alkyl, or phenyl, or R<3> and R<4> are bonded together to form C3-6 cycloalkyl in cooperation with the carbon atom bonded thereto; R<5> represents hydroxy, C1-6 alkoxy, or C1-6 alkylcarbonyloxy, or R<5> is bonded to R<6> to form a bond; R<6> represents hydrogen, or R<6> is bonded to R<5> to form a bond; and R<7> and R<8> each independently represent hydrogen or C1-6 alkyl, or R<7> and R<8> are bonded together to form pyrrolidinyl, imidazolidinyl, pyrazolidinyl, piperidyl, piperazinyl, etc. in cooperation with the nitrogen atom bonded thereto, or R<7> and R<8> are bonded together to form, in cooperation with the nitrogen atom bonded thereto, pyrrole ring optionally substituted with R<9> (where R<9> has the same meaning as R<1>).