发明名称 |
CYCLIC PEPTOLIDES |
摘要 |
Cyclic peptolides having the structure of a cyclosporin in which one amide linkage is replaced by an ester linkage are obtained by fermentation of fungal strains of the genus Cylindrotrichum Bonorden, or by cyclisation of a hydroxy-undecapeptide. The cyclic peptolides have immunosuppressive, anti-inflammatory and anti-parasitic properties. |
申请公布号 |
KR970010928(B1) |
申请公布日期 |
1997.07.02 |
申请号 |
KR19880007371 |
申请日期 |
1988.06.18 |
申请人 |
SANDOZ LIMITED |
发明人 |
DREYFUSS, MICHAEL MORRIS;SCHREIER, MAX H.;TSCHERTER, HANS;WENGER, ROLAND |
分类号 |
A61K;A61K38/00;A61P29/00;A61P37/06;C07K;C07K1/02;C07K1/113;C07K11/02;C07K14/37;C07K14/41;C12N;C12N1/14;C12P;C12P21/04;C12R;C12R1/645 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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